As the 19th and 21st U.S. Surgeon General, Dr. Vivek Murthy has faced some of the most difficult health crises in recent history. Murthy, appointed by Presidents Obama and Biden, shaped the federal response to the opioid epidemic, the rise of e-cigarettes, the Flint Michigan water crisis, and the COVID-19 pandemic. Recently, Murthy has written about and spoken on the negative health effects of loneliness, calling it an “epidemic” that increases the risk of early death and other social problems.